2011 ACCF/AHA/HRS Focused Update on the Management of Patients With Atrial Fibrillation (Updating the 2006 Guideline): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Wann LS, Curtis AB, January CT, et al.
J Am Coll Cardiol 2011;57:223-242.
Perspective: The following are 10 points to remember about these updated guidelines on the management of patients with atrial fibrillation (AF).
Metoprolol Versus Amiodarone in the Prevention of Atrial Fibrillation After Cardiac Surgery: A Randomized Trial
Halonen J, Loponen P, Jarvinen O, et al.
Ann Intern Med 2010;153:703-709.
Study Question: Is metoprolol as effective as amiodarone for preventing post-cardiac surgery atrial fibrillation (AF)?
Chest-Compression-Only Versus Standard Cardiopulmonary Resuscitation: A Meta-Analysis
Hupfl M, Selig HF, Nagele P.
Lancet 2010;376:1552-1557.
Study Question: Does chest-compression-only resuscitation (CCOR) improve outcomes compared to conventional cardiopulmonary resuscitation (CCPR)?
Mortality Resulting From Congenital Heart Disease Among Children and Adults in the United States, 1999 to 2006
Gilboa SM, Salemi JL, Nembhard WN, Fixler DE, Correa A.
Circulation 2010;122:2254-2263.
Study Question: What are the temporal trends of mortality resulting from congenital heart disease from 1999 to 2006?
Prediction of Cardiovascular Events in Statin-Treated Stable Coronary Patients by Lipid and Nonlipid Biomarkers
Arsenault BJ, Barter P, DeMicco DA, et al.
J Am Coll Cardiol 2011;57:63-69.
Study Question: What is the predictive value of lipid and nonlipid coronary heart disease (CHD) risk biomarker levels achieved during statin therapy, and the incidence of major cardiovascular events (MCVEs) in patients with stable CHD?
Multiple Biomarkers at Admission Significantly Improve the Prediction of Mortality in Patients Undergoing Primary Percutaneous Coronary Intervention for Acute ST-Segment Elevation Myocardial Infarction
Damman P, Beijk MA, Kuijt WJ, et al.
J Am Coll Cardiol 2011;57:29-36.
Study Question: What is the predictive ability of multiple biomarkers in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI)?
Association of Troponin T Detected With a Highly Sensitive Assay and Cardiac Structure and Mortality Risk in the General Population
de Lemos JA, Drazner MH, Omland T, et al.
JAMA 2010;304:2503-2512.
Study Question: What are the prevalence and determinants of detectable cardiac troponin T (cTnT) in the population, and are cTnT levels associated with pathological cardiac phenotypes and subsequent mortality
Troponin-Positive, MB-Negative Patients With Non–ST-Elevation Myocardial Infarction: An Undertreated but High-Risk Patient Group: Results From the National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network–Get With The Guidelines (NCDR ACTION-GWTG) Registry
Kontos MC, de Lemos JA, Ou FS, et al.
Am Heart J 2010;160:819-825.
Study Question: What is the effect of troponin (Tn) positive ([+]) status without concomitant elevations in creatine kinase-myocardial band (CK-MB) levels on treatment patterns and in-hospital clinical outcomes among non–ST-elevation myocardial infarction (NSTEMI) patients?
Telemonitoring in Patients With Heart Failure
Chaudhry SI, Mattera JA, Curtis JP, et al.
N Engl J Med 2010;363:2301-2309.
Study Question: Does telephone-based computerized monitoring improve outcomes in subjects with heart failure (HF)?
Depression as a Potential Modulator of Beta-Adrenergic–Associated Leukocyte Mobilization in Heart Failure Patients
Redwine LS, Wirtz PH, Hong S, et al.
J Am Coll Cardiol 2010;56:1720-1727.
Study Question: Clinical outcomes are worse for patients with heart failure (HF) presenting with symptoms of depression. Is sympathetically modulated immune dysregulation associated with depression one of the mechanisms leading to worse prognosis?
Meta-Analysis: Effect of B-Type Natriuretic Peptide Testing on Clinical Outcomes in Patients With Acute Dyspnea in the Emergency Setting
Lam LL, Cameron PA, Schneider HG, Abramson MJ, Muller C, Krum H.
Ann Intern Med 2010;153:728-735.
Study Question: Does B-type natriuretic peptide (BNP) or N-terminal BNP (NT-BNP) testing in patients presenting to the emergency room (ER) with acute dyspnea impact outcomes?
Fractional Flow Reserve for the Assessment of Nonculprit Coronary Artery Stenoses in Patients With Acute Myocardial Infarction
Ntalianis A, Sels JW, Davidavicius G, et al.
JACC Cardiovasc Intv 2010;3:1274-1281.
Study Question: What is the reliability of fractional flow reserve (FFR) of nonculprit coronary stenoses during percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI)?