The correct answer is D. Patients treated with tissue plasminogen activator for stroke are at high risk for intracranial hemorrhage. They should have frequent neurological checks for at least the first 24 hours. Every 6 hours (choice E) is not adequate.
Antiplatelet agents such as aspirin (choice A) and anticoagulants such as intravenous heparin (choice B) are contraindicated for 24 hours following tissue plasminogen activator administration.
Following the administration of tissue plasminogen activator, systolic blood pressure should be kept below 180 mm Hg to reduce the risk of intracranial hemorrhage. However, the blood pressure should not be medically lowered more than necessary as this will reduce blood flow to the brain (choice C).
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