Дефицит железа у пациентов с СД1 обнаруживается у каждого четвертого и ассоциируется с повышенным риском депрессии и сниженным качеством жизни:
Decreased serum iron (< 60µg/dl) and ferritin levels (< 50pg/nl) were observed in 18 (16.8%) and 28 (26.7%) patients, respectively. Anemia was present in 20 patients (18.34%). A high rate of depression was observed: 42.2% (WHO-5) and 40.7% (CES-D). The personal goals and current diabetes therapy satisfaction score (PWTSS) was significantly better in patients with sufficient iron status (ferritin level > 50pg/ml, p=0.018). Multiple regression analysis revealed iron status (p=0.03) to be an independent predictor for better PWTSS. Insufficient iron status correlated significantly with depression as measured by WHO-5 (p=0.044) and CES-D (p=0.029).
Type 1 diabetes patients in the current study were frequently depressive and reported an impaired QoL that associated with iron insufficiency. If confirmed a better awareness is needed for depression and ID in long standing disease.
---
Diabetes Res Clin Pract. 2019 Mar 29.
Iron deficiency in long standing type 1 diabetes mellitus and its association with depression and impaired quality of life.
Bergis D и соавт.
|