еще одна публикация о жд и фертильности из Хельсинки, которая показала, что у женщин с дефицитом железа (ферритин менее 30) введение 500 мг фериндзжекта повысило шансы на зачатие с 65% до 77%, в 3 раза снизило прерывание беременности и в 3 раза (до 51%) шансы на рождение ребенка:
In the model adjusted for age, use of preimplantation genetic testing for aneuploidy, and repeated iron infusions, treatment of iron deficiency with iron infusion was associated with a higher live birth rate (OR = 3.19; 95% CI = 2.21-4.66; p < 0.001).
In the model adjusted for age, reason for infertility, and total number of pregnancies, treatment of iron deficiency was associated with lower miscarriage rates (OR = 0.32; 95% Cl = 0.20-0.52; p < 0.001).
Conclusions: Filling of depleted iron stores was positively associated with conception results (higher number of pregnancies) and pregnancy outcomes (higher live birth rates and lower miscarriage rates), regardless of the assisted reproductive technology method used. Screening of iron status seems to be important in patients seeking help for infertility problems.
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Acta Obstet Gynecol Scand. 2025 Jan 16.
Association between iron deficiency and fertility
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