первый раз слышу про такие антитела при СКВ, но в литературе они описаны как люпус-нефрит антитела
Anti-C1q antibodies are also known as "lupus nephritis antibodies."
Since the nineties, Siegert et al. (14) and Haseley et al. (51) reported significant elevations of anti-C1qAb levels in SLE patients with kidney disease compared to those without kidney involvement, particularly in the months preceding the onset of lupus nephritis.
именно поражение почек при люпус нефрите описывают как причина hyporeninemic hypoaldosteronism
иногда нужно время между обнаружением антител и появлением люпус нефрита, но не у всех, а у одной трети
Anti-C1q were found in 33 of 83 patients (39%) without history of renal disease. 9 of the 33 patients with anti-C1q developed lupus nephritis. The median renal disease-free interval was 9 months.
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