Уровень Д-димера и рецидив тромбоза

[Dr.Vad]

Чем выше Д-димер при впервые выявленном ТГВ, тем выше риск рецидива: при цифрах менее 1.5 мкг/мл риск рецидива ниже в 2-3 раза, подробнее

During a median follow-up of 3.9-years, 84 patients experienced a recurrent VTE. The crude recurrence-rate was 1.7 (95%CI: 1.0-2.9) per 100 person-years in the lower quartile of d-dimer (≤1500 ng/mL), and 4.9 (95%CI: 3.9-6.1) per 100 person-years in the upper three quartiles combined, yielding an absolute risk difference of 3.2 per 100 person-years. Patients with d-dimer ≤1500 ng/mL had 54% lower recurrence-risk than patients with d-dimer >1500 ng/mL (HR: 0.46, 95%CI: 0.25-0.82). The association was particularly pronounced among patients with unprovoked events and deep vein thrombosis, showing a 66% (HR: 0.34, 95%CI: 0.15-0.74) and 68% (HR: 0.32, 95%CI: 0.14-0.71) lower recurrence-risk among patients with d-dimer ≤1500 ng/mL, respectively.
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D-dimer at venous thrombosis diagnosis is associated with risk of recurrence.
Bjоri E, Johnsen HS, Hansen JB, Braekkan SK.
J Thromb Haemost. 2017 Feb 6