Озон 2005 (Конференция)
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#4
11.10.2005, 00:36
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Свежак!!!
Infect Control Hosp Epidemiol. 2005 Sep;26(9):762-7. Related Articles, Links
A cluster of hepatitis C virus infections associated with ozone-enriched transfusion of autologous blood in Rome, Italy. Faustini A, Capobianchi MR, Martinelli M, Abbate I, Cappiello G, Perucci CA. Department of Epidemiology, Local Health Authority RM-E, via Santa Costanza n. 53, 00198 Rome, Italy. [Ссылки доступны только зарегистрированным пользователям ] OBJECTIVE: To describe an outbreak of hepatitis C virus (HCV). DESIGN: Retrospective cohort study. SETTING: Outpatient department of a hospital in Rome, Italy. PATIENTS: All 42 patients exposed to ozone therapy by autohemotherapy or intramuscular injection from January to June 2001. METHODS: Epidemiologic investigation, serologic analysis, and virus genotyping. RESULTS: Thirty-one (74%) of the patients agreed to participate in the study. Three (9.7%) had symptoms of HCV infection. This incidence rate was higher than the rate of 1.4 per 100,000 per year in the regional population. Six patients were positive for HCV antibodies and HCV RNA for a prevalence rate of 19.4%, which was much higher than the estimate of 0.9% in the population. Virus genotype 1b was found in two case-patients (one symptomatic) and 2c in four case-patients (two symptomatic), one of whom was known to have an HCV infection since 1986 and could have been the source of infection. The infected patients were all being exposed to ozone-enriched transfusions of autologous blood. Although the specific mode of transmission between patients was not detected, transmission probably occurred during one of the three busiest therapeutic sessions in the 6-month period. CONCLUSIONS: Transmission of HCV infection may occur during medical procedures with limited bleeding. Standard precautions must be applied in any healthcare setting; restricting the number of individuals treated during each therapeutic session could be an effective way of avoiding accidental transmission of infection. Evid Based Dent. 2005;6(2):34. Related Articles, Links No reliable evidence that ozone gas stops or reverses tooth decay. McComb D. 1Director of Comprehensive Care Programme, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada. Data sourcesThe Cochrane Oral Health Group's Trials Register, Cochrane Central Register of Controlled Trials, Medline and Premedline, Embase, CINAHL (Cumulative Index to nursing and Allied Health Literature)l and the Allied and Complementary Medicine Database were searched. The journal Quintessence was searched by hand and KaVo Dental (Biberach, Germany) manufacturers of HealOzone apparatus were contacted for any additional published or unpublished trials.Study selectionInclusion was assessed independently by at least two reviewers. Trials were only included if they met the following criteria: randomisation in a controlled trial; single surface in vivo carious lesion accessible to ozone application; clear allocation concealment; ozone application to the lesions in the intervention group; no such application of ozone in the control group; and outcomes measured after at least 6 months.Data extraction and synthesisReviewers independently extracted information in duplicate. A paucity of comparable data did not allow meta-analytic pooling of the included studies.ResultsThree trials were included, with a combined total of 432 randomised lesions (137 participants). Forty-two conference papers, abstracts and posters were excluded (from an unknown number of studies). The risk of bias in all studies appeared high. The analyses of all three studies were conducted at the level of the lesion, which is not independent of the person. For this reason, pooling of data was not appropriate or attempted. Individual studies showed inconsistent effects of ozone on caries, across different measures of caries progression or regression. Few secondary outcomes were reported, but one trial reported an absence of adverse events.ConclusionsGiven the high risk of bias in the available studies and lack of consistency between different outcome measures, there is no reliable evidence that application of ozone gas to the surface of decayed teeth stops or reverses the decay process. There is a fundamental need for more evidence of appropriate rigour and quality before the use of ozone can be accepted into mainstream primary dental care or can be considered a viable alternative to current Int J Biol Macromol. 2005 Jul;36(1-2):61-5. Related Articles, Links Chemical kinetics measurements on the reaction between blood and ozone. Cataldo F, Gentilini L. Soc. Lupi Chemical Research, Via Casilina 1626/A, 00133 Rome, Italy. [Ссылки доступны только зарегистрированным пользователям ] The pseudofirst-order ozonization rate constant of whole bovine blood has been measured in comparison to that of free haemin. The free prosthetic group haemin (which has also the central iron atom in the oxidized form) shows k values in the range of 0.20-0.03 s(-1) while the haeme groups inside haemoglobin protein and contained in the whole blood sample show slightly lower k values, just in the range of 0.10-0.02 s(-1). It has been found that ozone even with whole blood reacts specifically with haemoglobin of the red cells because it is adsorbed selectively on the iron atoms of the haeme prosthetic groups of haemoglobin. The absorption implies the oxidation of the central iron atom of the haeme groups with formation of methaemoglobin followed by an oxidative fission of the haeme rings. The other blood components do not exert any significant protection to the reaction between ozone and haemoglobin, which appear extremely specific and selective like the reaction between CO or HCN and haemoglobin. By analogy with the behaviour of these other gases ozone may be classified as a blood poison. The results of this work are discussed in the frame of the risks connected to the ozonotherapy and autohaemotherapy involving the blood ozonization of human or animal subjects and the re-injection of ozonized blood into the bodies. |
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#5
11.10.2005, 08:25
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Во всем мире определенный процент новых инфицирований гепатитом происходит при переливании крови. Не исключено, что при тех или иных санитарно-гигиенических нарушениях, такое возможно и при манипуляциях с озонированной кровью. Но уже не в первый раз спрашиваю, причем здесь сама ОТ?
По второму пункту. На этом форуме уже неоднократно сообщалось, что озон при кариесе это разработка английских стоматологов, которую они активно продвигают. В России она не практикуется. И, несмотря на то, что именно для кариеса имеется самое значительное количество двойных, слепых, рандомизированных с наблюдением за пациентами после лечения от года и выше, лично у меня эта методика, пока, вызывает большие сомнения. Зачем опять возвращаться к этому вопросу? То же можно сказать и по третьей ссылки. В сотый раз отмечаю, что рассуждать о сравнительном влиянии озона на форменные элементы крови без точных дозировок, концентраций – бессмысленно, безграмотно. Как правило, в таких работах in vitro используются дозы значительно превышающие используемые при ОТ. Зачем, вообще, этот торжествующий «Свежак!!!» - подбор чернухи, когда модератор практически полностью «заморозил» свой форум, чтобы не раздражать местных авторитетов? |
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#6
11.10.2005, 08:39
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Уважаемый Владимир Яковлевич, а Вы правда верите, что являетесь модератором этого форума?
"Практически полностью "заморозил"" -  "Мы с тобою бежали из рая практически босиком" - перл группы "Чайф", почему то исполняется скорбящим голосом. |
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#7
11.10.2005, 19:36
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Цитата:
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Для Яны Студенцовой.
Линейный вид
